Comparative observations of reserpine and syrosingopine.

@article{Winer1960ComparativeOO,
  title={Comparative observations of reserpine and syrosingopine.},
  author={B. Winer and B. Sahay},
  journal={The New England journal of medicine},
  year={1960},
  volume={263},
  pages={
          1165-9
        }
}
IN animals, syrosingopine, a synthetic derivative of reserpine, has hypotensive activity equivalent to that of reserpine, but markedly less sedative effect.1 In man, syrosingopine has been reported to have hypotensive effects and virtually no side effects when administered orally in doses of 1 to 5 mg. a day.2 3 4 5 6 Our studies indicate that syrosingopine does not have hypotensive potency equivalent to that of reserpine when administered orally in human hypertensive subjects. The evidence… Expand

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