Comparative nucleotide and amino acid sequence analysis of the sequence-specific RNA-binding rotavirus nonstructural protein NSP3.

@article{Rao1995ComparativeNA,
  title={Comparative nucleotide and amino acid sequence analysis of the sequence-specific RNA-binding rotavirus nonstructural protein NSP3.},
  author={Chamarty D. V. P. Rao and Manjula Das and P Ilango and R Lalwani and Bachoti S. Rao and Krishne Gowda},
  journal={Virology},
  year={1995},
  volume={207 1},
  pages={327-33}
}
NSP3, an acidic nonstructural protein, encoded by gene 7 has been implicated as the key player in the assembly of the 11 viral plus-strand RNAs into the early replication intermediates during rotavirus morphogenesis. To date, the sequence of NSP3 from only three animal rotaviruses (SA11, SA114F, and bovine UK) has been determined and that from a human strain has not been reported. To determine the genetic diversity among gene 7 alleles from group A rotaviruses, the nucleotide sequence of the… CONTINUE READING