Comparative morphological and biological studies on the itraconazole- and ketoconazole-resistant mutants of Cryptococcus neoformans.

Abstract

Studies were carried out on the resistance in vitro of Cryptococcus neoformans to the oral antifungal drugs itraconazole and ketoconazole. None of the six sensitive strains tested developed resistance to itraconazole or ketoconazole by serial transfer on Sabouraud's glucose agar plates containing increasing concentrations of either drug. One mutant… (More)

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@article{Iwata1990ComparativeMA, title={Comparative morphological and biological studies on the itraconazole- and ketoconazole-resistant mutants of Cryptococcus neoformans.}, author={Koichi Iwata and Takashi Yamashita and Mariko Ohsumi and Masanori Baba and Nobuko Naito and A. Taki and Naoto Yamada}, journal={Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology}, year={1990}, volume={28 1}, pages={77-90} }