Comparative metagenomic analysis of plasmid encoded functions in the human gut microbiome

@inproceedings{Jones2009ComparativeMA,
  title={Comparative metagenomic analysis of plasmid encoded functions in the human gut microbiome},
  author={Brian V Jones and Funing Sun and Julian R Marchesi},
  booktitle={BMC Genomics},
  year={2009}
}
Little is known regarding the pool of mobile genetic elements associated with the human gut microbiome. In this study we employed the culture independent TRACA system to isolate novel plasmids from the human gut microbiota, and a comparative metagenomic analysis to investigate the distribution and relative abundance of functions encoded by these plasmids in the human gut microbiome. Novel plasmids were acquired from the human gut microbiome, and homologous nucleotide sequences with high… CONTINUE READING
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