Comparative mapping of the region of human chromosome 7 deleted in williams syndrome.

@article{DeSilva1999ComparativeMO,
  title={Comparative mapping of the region of human chromosome 7 deleted in williams syndrome.},
  author={Udaya DeSilva and Hillary F. Massa and Barbara J. Trask and Eric D. Green},
  journal={Genome research},
  year={1999},
  volume={9 5},
  pages={428-36}
}
Williams syndrome (WS) is a complex developmental disorder resulting from the deletion of a large (approximately 1.5-2 Mb) segment of human chromosome 7q11.23. Physical mapping studies have revealed that this deleted region, which contains a number of known genes, is flanked by several large, nearly identical blocks of DNA. The presence of such highly related DNA segments in close physical proximity to one another has hampered efforts to elucidate the precise long-range organization of this… CONTINUE READING

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