Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routes

@inproceedings{Teeguarden2014ComparativeIO,
  title={Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routes},
  author={Justin G. Teeguarden and Vladimir B Mikheev and Kevin R. Minard and William C Forsythe and Wei Wang and Gaurav Sharma and Norman Karin and Susan C. Tilton and Katrina M. Waters and Bahman Asgharian and Owen R Price and Joel G. Pounds and Brian D. Thrall},
  booktitle={Particle and Fibre Toxicology},
  year={2014}
}
Toxicity testing the rapidly growing number of nanomaterials requires large scale use of in vitro systems under the presumption that these systems are sufficiently predictive or descriptive of responses in in vivo systems for effective use in hazard ranking. We hypothesized that improved relationships between in vitro and in vivo models of experimental toxicology for nanomaterials would result from placing response data in vitro and in vivo on the same dose scale, the amount of material… CONTINUE READING
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The long view of nanotechnology development: the National Nanotechnology Initiative at 10 years

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