Comparative investigation of the effect of moclobemide and toloxatone on monoamine oxidase activity and psychometric performance in healthy subjects

@article{Dingemanse2005ComparativeIO,
  title={Comparative investigation of the effect of moclobemide and toloxatone on monoamine oxidase activity and psychometric performance in healthy subjects},
  author={Jasper Dingemanse and Ivan Berlin and Christine Payan and H. M. Thiede and Alain Jacques Puech},
  journal={Psychopharmacology},
  year={2005},
  volume={106},
  pages={S68-S70}
}
The effects of moclobemide and toloxatone, two reversible monoamine oxidase-A inhibitors, on biochemical parameters that reflect monoamine metabolism and on psychomotor performance parameters were investigated in a study in 12 healthy volunteers. Treatments were given double-blind in a randomised, placebo-controlled cross-over design, with 1 week wash-out between the treatments. Drugs were given thrice daily in the following doses: moclobemide 150-150-150 mg and toloxatone 400-200-400 mg. All… Expand
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