Comparative intraperitoneal pharmacokinetics of three platinum analogues

@article{Lind1991ComparativeIP,
  title={Comparative intraperitoneal pharmacokinetics of three platinum analogues},
  author={MichaelJ. Lind and David V. J. Murphy and H I Sharma and Nigel D. Tinker and Andrew Lee Smith and C. A. Mcauliffe and Derek Crowther},
  journal={Cancer Chemotherapy and Pharmacology},
  year={1991},
  volume={28},
  pages={315-317}
}
SummaryThe pharmakokinetic profiles of intraperitoneally infused platinum analogues were determined in 13 women exhibiting minimal residual disease following surgery and systemic chemotherapy for epithelial ovarian cancer of fallopian tube carcinoma by following the disposition of tracer doses of195mPt radiolabel. Six patients received iproplatin, four were given cisplatin and three received carboplatin. The present data demonstrate no difference in the disposition of total platinum between… CONTINUE READING
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