Comparative in vivo approaches for selective adenovirus-mediated gene delivery to the placenta.

@article{Xing2000ComparativeIV,
  title={Comparative in vivo approaches for selective adenovirus-mediated gene delivery to the placenta.},
  author={Aihua Xing and Pascal Boileau and Mich{\`e}le Ca{\"u}zac and J. C. Challier and Jean Girard and Sylvie Hauguel-de Mouzon},
  journal={Human gene therapy},
  year={2000},
  volume={11 1},
  pages={167-77}
}
Gene delivery to the placenta is one potential way of specifically modifying placental biological processes and fetal development. The aim of this study was to determine the most efficient and least invasive route of placental adenovirus delivery. The feasibility of adenovirus-mediated gene transfer to the rat placenta was addressed by maternal intravenous or direct intraplacental injection of adenoviral vectors expressing the glucose transporter GLUT3, a noncirculating integral membrane… CONTINUE READING

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