Comparative in vitro and in vivo antimicrobial activities of sitafloxacin, gatifloxacin and moxifloxacin against Mycobacterium avium.

@article{Sano2011ComparativeIV,
  title={Comparative in vitro and in vivo antimicrobial activities of sitafloxacin, gatifloxacin and moxifloxacin against Mycobacterium avium.},
  author={Chiaki Sano and Yutaka Tatano and Toshiaki Shimizu and Seiko Yamabe and Katsumasa Sato and Haruaki Tomioka},
  journal={International journal of antimicrobial agents},
  year={2011},
  volume={37 4},
  pages={296-301}
}
Moxifloxacin exhibits therapeutic activity against Mycobacterium avium infection in mice. Since not only moxifloxacin but also another 8-methoxy quinolone, gatifloxacin, and a C-8-chloro quinolone, sitafloxacin, show favourable antimycobacterial activity in vitro, their anti-M. avium activities were compared in vivo. Minimum inhibitory concentrations (MICs), minimum bactericidal concentrations (MBCs) and mutant prevention concentrations (MPCs) of the test quinolones for M. avium were determined… CONTINUE READING

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