Comparative in vitro activity of the new erythromycin derivative dirithromycin against gram-positive bacteria isolated from cancer patients

@article{Rolston1990ComparativeIV,
  title={Comparative in vitro activity of the new erythromycin derivative dirithromycin against gram-positive bacteria isolated from cancer patients},
  author={Kenneth V. I. Rolston and D. H. W. Ho and Barbara Leblanc and Gerald Paul Bodey},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1990},
  volume={9},
  pages={30-33}
}
The in vitro activity of dirithromycin (LY-237216), a new macrolide erythromycin derivative, was compared to that of four other agents (clarithromycin, erythromycin, roxithromycin, clindamycin) against 334 gram-positive isolates obtained from cancer patients. Dirithromycin was similar in potency and antimicrobial spectrum to the other agents tested. It was very active against beta-haemolytic streptococci andStreptococcus pneumoniae, and moderately active against penicillin and methicillin… CONTINUE READING