Comparative in vitro activity of norfloxacin against urinary tract pathogens

  title={Comparative in vitro activity of norfloxacin against urinary tract pathogens},
  author={David H. Haase and B A Urias and Godfrey Harding and Allan Ronald},
  journal={European Journal of Clinical Microbiology},
The in vitro activity of norfloxacin (MK366) against 477 aerobic gram-negative and gram-positive clinical isolates was compared to that of nalidixic acid, nitrofurantoin, ampicillin, cephalexin, trimethoprim, sulfamethoxazole, and the combination trimethoprim-sulfamethoxazole. Norfloxacin was more active than the other agents against all gram-negative organisms tested. Minimal inhibitory concentrations (MICs) ofPseudomonas aeruginosa were ⩽ 0.125–32 mg/l with 90 % inhibited (MIC90) by 4 mg/l… CONTINUE READING


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