Comparative in vitro activities of third-generation cephalosporins.

  title={Comparative in vitro activities of third-generation cephalosporins.},
  author={Robert J. Fass},
  journal={Archives of internal medicine},
  volume={143 9},
The in vitro susceptibilities of 823 clinical isolates to eight third-generation cephalosporin and cephalosporinlike antibiotics were studied. All eight antibiotics were more active and had broader spectrums of activity against gram-negative bacilli and anaerobes than older derivatives; however, they were less active against gram-positive cocci. Cefotaxime sodium, cefmenoxime hydrochloride, ceftriaxone disodium, and ceftizoxime sodium had similar activities. Cefoperazone sodium was more active… CONTINUE READING