Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte Stress 1 gene promoter

@article{Ounzain2007ComparativeIS,
  title={Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte Stress 1 gene promoter},
  author={Samir Ounzain and Caroline S. Dacwag and Nilesh J. Samani and Anthony N Imbalzano and Nelson W. S. Chong},
  journal={BMC Molecular Biology},
  year={2007},
  volume={9},
  pages={50 - 50}
}
BackgroundMyocyte stress 1 (MS1) is a striated muscle actin binding protein required for the muscle specific activity of the evolutionary ancient myocardin related transcription factor (MRTF)/serum response factor (SRF) transcriptional pathway. To date, little is known about the molecular mechanisms that govern skeletal muscle specific expression of MS1. Such mechanisms are likely to play a major role in modulating SRF activity and therefore muscle determination, differentiation and… CONTINUE READING

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