Comparative immunogenicity of trivalent influenza vaccine administered by intradermal or intramuscular route in healthy adults.

@article{Belshe2007ComparativeIO,
  title={Comparative immunogenicity of trivalent influenza vaccine administered by intradermal or intramuscular route in healthy adults.},
  author={Robert B . Belshe and Frances K. Newman and Ken Wilkins and Irene L. Graham and Elizabeth Babusis and Marian Ewell and Sharon E. Frey},
  journal={Vaccine},
  year={2007},
  volume={25 37-38},
  pages={
          6755-63
        }
}
The present study was undertaken with controls using equal doses ID and IM plus the standard full dose IM to assess the role of route of vaccine in immunogenicity of inactivated influenza vaccine. The study was a prospective, randomized, active-controlled, open label clinical trial conducted in healthy young adult outpatients to compare the effect of route (IM versus ID) on antibody responses to influenza vaccine. Volunteers received 3, 6 or 9 microg of vaccine by ID or IM route; 15 microg IM… CONTINUE READING
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