Comparative human and mouse antibody responses against tetanus toxin at clonal level.

Abstract

Tetanus is a highly fatal disease caused by tetanus neurotoxin (TeNT) and remains a major threat to human and animal health, despite preventive strategies. TeNT is composed of heavy and light chain linked by a disulfide bond. The antibody response to TeNT is polyclonal and directed to multiple epitopes within both the light and heavy chains, leading to… (More)
DOI: 10.3109/1547691X.2015.1046572

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