Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation.

@article{Hooper1998ComparativeHE,
  title={Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation.},
  author={Kenny A Hooper and Natalie D Macon and Joachim Kohn},
  journal={Journal of biomedical materials research},
  year={1998},
  volume={41 3},
  pages={443-54}
}
Previous studies demonstrated that poly(DTE carbonate) and poly (DTE adipate), two tyrosine-derived polymers, have suitable properties for use in biomedical applications. This study reports the evaluation of the in vivo tissue response to these polymers in comparison to poly(L-lactic acid) (PLLA). Typically, the biocompatibility of a material is determined through histological evaluations as a function of implantation time in a suitable animal model. However, due to changes that can occur in… CONTINUE READING
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