Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury

  title={Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury},
  author={Cheau Yih Tan and Tzuen Yih Saw and Chee Wai Fong and Han Kiat Ho},
  booktitle={Redox biology},
Oxidative stress plays a major part in the pathogenesis of drug-induced liver injury. Yet, overcoming it with other xenobiotics impose additional risks. In this study, we consider the use of natural-occurring and purified Vitamin E analogs as hepatoprotective agents. Vitamin E is well-known for its intrinsic antioxidant property even though the differential effect of specific analogs of tocopherol (TP) and tocotrienol (T3) is still not ascertained. This study investigates the protective effect… CONTINUE READING
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