Comparative genomics of the neglected human malaria parasite Plasmodium vivax

  title={Comparative genomics of the neglected human malaria parasite Plasmodium vivax},
  author={Jane M. Carlton and John H Adams and Joana C. Silva and Shelby L. Bidwell and Hernan A Lorenzi and Elisabet Caler and Jonathan Crabtree and Samuel V. Angiuoli and Emilio Fernando Merino and Paolo Amedeo and Qin Cheng and Richard M. R. Coulson and Brendan Crabb and Hernando del Portillo and Kobby Essien and Tamara V. Feldblyum and Carmen Fern{\'a}ndez-Becerra and Paul R Gilson and Amy H. Gueye and Xiang Guo and Simon Kang’a and Taco W A Kooij and Michael Korsinczky and Esmeralda V.-S. Meyer and Vishvanath M. Nene and Ian Paulsen and O. White and Stuart A. Ralph and Qinghu Ren and Tobias J. Sargeant and Steven L Salzberg and Christian J. Stoeckert and Steven A. Sullivan and M{\'a}rcio Massao Yamamoto and Stephen L Hoffman and Jennifer R. Wortman and Malcolm J. Gardner and Mary Galinski and John W. Barnwell and Claire Fraser-Liggett},
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the ∼515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms and often causes relapses months after a primary infection has cleared. Despite its importance as a major human pathogen, P. vivax is little studied because it cannot be propagated continuously in the laboratory except in non-human primates. We sequenced the genome of P. vivax to shed… CONTINUE READING
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