Comparative genomics approach to the expression of figalpha, one of the earliest marker genes of oocyte differentiation in medaka (Oryzias latipes).

@article{Kanamori2008ComparativeGA,
  title={Comparative genomics approach to the expression of figalpha, one of the earliest marker genes of oocyte differentiation in medaka (Oryzias latipes).},
  author={Akira Kanamori and Keiko Toyama and Sachiko Kitagawa and Aya Kamehara and Tomoya Higuchi and Yusuke Kamachi and Masato Kinoshita and H. Hori},
  journal={Gene},
  year={2008},
  volume={423 2},
  pages={
          180-7
        }
}
We analyzed molecular cascades of sex differentiation in medaka gonads by examining the transcriptional regulation of the oocyte-expressed gene, figalpha. We first confirmed that figalpha is one of the earliest marker genes of oocyte differentiation by quantitative RT-PCR and in situ hybridization. Expression of putative figalpha target genes, zpc4 and zpb, followed that of figalpha. A meiosis-specific gene, scp3, showed expression temporally and spatially similar to figalpha. To characterize… CONTINUE READING
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