Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human Chromosome 7q11.23

@article{Martindale2000ComparativeGS,
  title={Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human Chromosome 7q11.23},
  author={Duane W. Martindale and Michael D. Wilson and Diana Wang and Robert D. Burke and Xianming Chen and Vincent Duronio and Ben F. Koop},
  journal={Mammalian Genome},
  year={2000},
  volume={11},
  pages={890-898}
}
Abstract. Williams syndrome (WS) is a complex neurodevelopmental disorder arising from a microdeletion at Chr band 7q11.23, which results in a hemizygous condition for a number of genes. Within this region we have completely characterized 200 kb containing the genes LIMK1, WBSCR1, and RFC2. Evidence was also found for WBSCR5 in this region, but not the previously proposed genes WSCR2 and WSCR6. The syntenic region in mouse was also sequenced (115 kb) and characterized, and a comparative… 

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