Comparative genomic reconstruction of transcriptional regulatory networks in bacteria.

  title={Comparative genomic reconstruction of transcriptional regulatory networks in bacteria.},
  author={Dmitry A. Rodionov},
  journal={Chemical reviews},
  volume={107 8},
Microorganisms in most ecological niches are constantly exposed to variations of many environmental factors, including temperature; oxygen, nutrient, and water availability; presence of toxic compounds; and interaction with other organisms. Changing gene-expression patterns is a major adaptive response to these variations. Expression of genes in bacteria is controlled by a variety of mechanisms based on the level of transcription or translation. In most cases, the switch in gene expression is… CONTINUE READING
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