Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris

@article{Berka2011ComparativeGA,
  title={Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris},
  author={Randy M. Berka and Igor V. Grigoriev and Robert Otillar and A. M. Salamov and Jane Grimwood and Ian S. Reid and Nadeeza Ishmael and Tricia John and Corinne Darmond and Marie-Claude Moisan and Bernard Henrissat and Pedro M Coutinho and Vincent Lombard and Donald O Natvig and Erika Lindquist and Jeremy Schmutz and Sara Lucas and Paul R. Harris and Justin Powlowski and Annie Bellemare and David L. Taylor and Gregory Butler and Ronald P. de Vries and Iris E Allijn and Joost van den Brink and Sophia C Ushinsky and Reginald Storms and A. D. J. Powell and Ian T. Paulsen and Liam Davin Hunt Elbourne and Scott E Baker and Jon Karl Magnuson and Sylvie LaBoissi{\`e}re and Amberlie Clutterbuck and Diego Mart{\'i}nez and Mark Wogulis and Alfredo L{\'o}pez De Le{\'o}n and Michael Willard Rey and Adrian Tsang},
  journal={Nature Biotechnology},
  year={2011},
  volume={29},
  pages={922-927}
}
Thermostable enzymes and thermophilic cell factories may afford economic advantages in the production of many chemicals and biomass-based fuels. Here we describe and compare the genomes of two thermophilic fungi, Myceliophthora thermophila and Thielavia terrestris. To our knowledge, these genomes are the first described for thermophilic eukaryotes and the first complete telomere-to-telomere genomes for filamentous fungi. Genome analyses and experimental data suggest that both thermophiles are… CONTINUE READING
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