Comparative genome analysis of the pathogenic spirochetes Borrelia burgdorferi and Treponema pallidum.

Abstract

A comparative analysis of the predicted protein sequences encoded in the complete genomes of Borrelia burgdorferi and Treponema pallidum provides a number of insights into evolutionary trends and adaptive strategies of the two spirochetes. A measure of orthologous relationships between gene sets, termed the orthology coefficient (OC), was developed. The… (More)

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Cite this paper

@article{Subramanian2000ComparativeGA, title={Comparative genome analysis of the pathogenic spirochetes Borrelia burgdorferi and Treponema pallidum.}, author={Gangadharan Mani Subramanian and Eugene V. Koonin and L. Aravind}, journal={Infection and immunity}, year={2000}, volume={68 3}, pages={1633-48} }