Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas.

@article{Gutmann2002ComparativeGE,
  title={Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas.},
  author={David H. Gutmann and Nicole M. HedrickN.M. Hedrick and Jun Li and Rakesh Nagarajan and Arie Perry and Mark A. Watson},
  journal={Cancer research},
  year={2002},
  volume={62 7},
  pages={
          2085-91
        }
}
Pilocytic astrocytomas (PAs) are WHO grade I brain tumors that do not typically progress to more malignant grades of astrocytoma. Whereas there have been significant advances in the molecular genetics of high-grade astrocytomas, relatively little is known about the genetic changes associated with PA formation. In an effort to better characterize these low-grade neoplasms, we compared the gene expression profiles of six sporadic and two neurofibromatosis 1-associated PAs with other tissues and… CONTINUE READING

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Expression microarray analysis: pilocytic astrocytomas and oligodendrogliomas compared with anaplastic astrocytomas

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