Comparative experiments to examine the effects of heating on vegetative cells and spores of Clostridium perfringens isolates carrying plasmid genes versus chromosomal enterotoxin genes.

@article{Sarker2000ComparativeET,
  title={Comparative experiments to examine the effects of heating on vegetative cells and spores of Clostridium perfringens isolates carrying plasmid genes versus chromosomal enterotoxin genes.},
  author={Mahfuzur Rahman Sarker and Robert P. Shivers and Stanley Sparks and Vijay K Juneja and Bruce A McClane},
  journal={Applied and environmental microbiology},
  year={2000},
  volume={66 8},
  pages={
          3234-40
        }
}
Clostridium perfringens enterotoxin (CPE) is an important virulence factor for both C. perfringens type A food poisoning and several non-food-borne human gastrointestinal diseases. Recent studies have indicated that C. perfringens isolates associated with food poisoning carry a chromosomal cpe gene, while non-food-borne human gastrointestinal disease isolates carry a plasmid cpe gene. However, no explanation has been provided for the strong associations between certain cpe genotypes and… CONTINUE READING
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