Comparative evaluation of two two-dimensional gel electrophoresis image analysis software applications using synovial fluids from patients with joint disease
@article{Arora2005ComparativeEO, title={Comparative evaluation of two two-dimensional gel electrophoresis image analysis software applications using synovial fluids from patients with joint disease}, author={Pankaj S. Arora and H. Yamagiwa and A. Srivastava and Mark E. Bolander and G. Sarkar}, journal={Journal of Orthopaedic Science}, year={2005}, volume={10}, pages={160-166} }
The proteomic composition of synovial fluid (SF) may hold clues to understanding the molecular basis of arthritis. However, the highly viscous nature and proteomic complexity of SF present a challenge when analyzing results obtained by two-dimensional gel electrophoresis (2D-GE). Several software applications are available for analyzing 2D-GE images. Despite inherent strengths and weaknesses, no comparison between these applications has been reported using SF or any human fluid specimens. We… CONTINUE READING
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