Comparative evaluation of two two-dimensional gel electrophoresis image analysis software applications using synovial fluids from patients with joint disease

@article{Arora2005ComparativeEO,
  title={Comparative evaluation of two two-dimensional gel electrophoresis image analysis software applications using synovial fluids from patients with joint disease},
  author={Pankaj S. Arora and H. Yamagiwa and A. Srivastava and Mark E. Bolander and G. Sarkar},
  journal={Journal of Orthopaedic Science},
  year={2005},
  volume={10},
  pages={160-166}
}
  • Pankaj S. Arora, H. Yamagiwa, +2 authors G. Sarkar
  • Published 2005
  • Computer Science, Medicine
  • Journal of Orthopaedic Science
  • The proteomic composition of synovial fluid (SF) may hold clues to understanding the molecular basis of arthritis. However, the highly viscous nature and proteomic complexity of SF present a challenge when analyzing results obtained by two-dimensional gel electrophoresis (2D-GE). Several software applications are available for analyzing 2D-GE images. Despite inherent strengths and weaknesses, no comparison between these applications has been reported using SF or any human fluid specimens. We… CONTINUE READING
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    References

    SHOWING 1-7 OF 7 REFERENCES
    Two-dimensional gel electrophoresis of synovial fluid: method for detecting candidate protein markers for osteoarthritis
    • 48
    Better approaches to finding the needle in a haystack: Optimizing proteome analysis through automation
    • M. Lopez
    • Biology, Medicine
    • Electrophoresis
    • 2000
    • 110
    • Highly Influential
    Proteomics: Capacity versus utility
    • 148
    • Highly Influential