Comparative evaluation of possible ocular photochemical toxicity of fluoroquinolones meant for ocular use in experimental models.

@article{Velpandian2006ComparativeEO,
  title={Comparative evaluation of possible ocular photochemical toxicity of fluoroquinolones meant for ocular use in experimental models.},
  author={Thirumurthy Velpandian and Rashmi Bankoti and Sadia Humayun and Alok Kumar Ravi and Shanthi Santhosh Kumari and Nihar Ranjan Biswas},
  journal={Indian journal of experimental biology},
  year={2006},
  volume={44 5},
  pages={387-91}
}
Fluoroquinolones (FQs) are extensively used in bacterial keratitis and other intraocular infections. Since eye is constantly exposed to light, incidence of ocular phototoxicity due to commonly used FQs is of great interest for their safe use. Phototoxicity of commonly used FQs (ciprofloxacin, lomefloxacin, pefloxacin, ofloxacin, sparfloxacin and gatifloxacin), has been evaluated by using HET-CAM-UV model (Photo Hen Egg Test-C Chorioallantoic Membrane model). This study was further extended by… CONTINUE READING

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