Comparative evaluation of freeze-dried and liquid antigens in the direct agglutination test for serodiagnosis of visceral leishmaniasis (ITMA-DAT/VL).

@article{Jacquet2006ComparativeEO,
  title={Comparative evaluation of freeze-dried and liquid antigens in the direct agglutination test for serodiagnosis of visceral leishmaniasis (ITMA-DAT/VL).},
  author={Diane Jacquet and Marleen Boelaert and Jill Seaman and Suman Rijal and Shyam Sundar and Joris Menten and Eddy Magnus},
  journal={Tropical medicine & international health : TM & IH},
  year={2006},
  volume={11 12},
  pages={1777-84}
}
OBJECTIVE The direct agglutination test (DAT) for visceral leishmaniasis (VL) with liquid (LQ) antigen is known to be only moderately reproducible because of inter-observer and batch-to-batch variability as well as its sensitivity to temperature and shaking during transport. We evaluated a DAT with freeze-dried (FD) antigen and compared it with the LQ antigen version. METHODS Blood samples of clinical VL suspects and healthy endemic controls were collected in Sudan, Nepal and India. Both test… CONTINUE READING

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