Comparative efficacy of acellular pertussis vaccines: an analysis of recent trials.

@article{Cherry1997ComparativeEO,
  title={Comparative efficacy of acellular pertussis vaccines: an analysis of recent trials.},
  author={James D. Cherry},
  journal={The Pediatric infectious disease journal},
  year={1997},
  volume={16 4 Suppl},
  pages={S90-6}
}
Diphtheria-tetanus-acellular pertussis vaccines have been licensed in the United States since 1991. Compared with the whole cell pertussis component diphtheria-tetanus-pertussis vaccine, the diphtheria-tetanus-acellular pertussis vaccines were found in reactogenicity and immunogenicity studies to be immunogenic with respect to their specific antigen content and to be associated with less severe and less frequent adverse reactions. A case definition of pertussis was developed by the World Health… CONTINUE READING
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