Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia.

@article{Farnier1994ComparativeEA,
  title={Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia.},
  author={Michel Farnier and Françoise Bonnefous and N. Debbas and A Carson Irvine},
  journal={Archives of internal medicine},
  year={1994},
  volume={154 4},
  pages={
          441-9
        }
}
BACKGROUND Few studies have been performed to compare fenofibrate, a second-generation fibrate, and simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. This study was aimed to compare the efficacy of both drugs in reducing atherogenic risk factors in type IIa or IIb hyperlipidemia. METHODS Sixty-three patients entered this single-center, double-blind, crossover trial. Sixty patients (32 with type IIa and 28 with type IIb hyperlipidemia) were randomized to treatment for 3… CONTINUE READING
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