Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis.

@article{Cipriani2011ComparativeEA,
  title={Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis.},
  author={Andrea Cipriani and Corrado Barbui and Georgia Salanti and Jennifer M Rendell and Rachel Mary Brown and Sarah Stockton and Marianna Purgato and Loukia M Spineli and Guy M. Goodwin and John R. Geddes},
  journal={Lancet},
  year={2011},
  volume={378 9799},
  pages={1306-15}
}
BACKGROUND Conventional meta-analyses have shown inconsistent results for efficacy of pharmacological treatments for acute mania. We did a multiple-treatments meta-analysis, which accounted for both direct and indirect comparisons, to assess the effects of all antimanic drugs. METHODS We systematically reviewed 68 randomised controlled trials (16,073 participants) from Jan 1, 1980, to Nov 25, 2010, which compared any of the following pharmacological drugs at therapeutic dose range for the… CONTINUE READING
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