Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

@article{Cipriani2009ComparativeEA,
  title={Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis},
  author={Andrea Cipriani and Toshiaki Furukawa and Georgia Salanti and John R. Geddes and Julian P. T. Higgins and Rachel Churchill and Norio Watanabe and Atsuo Nakagawa and Ichiro M. Omori and Hugh McGuire and Michele Tansella and Corrado Barbui},
  journal={The Lancet},
  year={2009},
  volume={373},
  pages={746-758}
}
BACKGROUND Conventional meta-analyses have shown inconsistent results for efficacy of second-generation antidepressants. We therefore did a multiple-treatments meta-analysis, which accounts for both direct and indirect comparisons, to assess the effects of 12 new-generation antidepressants on major depression. METHODS We systematically reviewed 117 randomised controlled trials (25 928 participants) from 1991 up to Nov 30, 2007, which compared any of the following antidepressants at… Expand
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