Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

  title={Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis},
  author={A. Cipriani and T. Furukawa and G. Salanti and J. Geddes and C. Barbui},
  journal={The Lancet},
  • A. Cipriani, T. Furukawa, +2 authors C. Barbui
  • Published 2009
  • Medicine
  • The Lancet
  • BACKGROUND Conventional meta-analyses have shown inconsistent results for efficacy of second-generation antidepressants. We therefore did a multiple-treatments meta-analysis, which accounts for both direct and indirect comparisons, to assess the effects of 12 new-generation antidepressants on major depression. METHODS We systematically reviewed 117 randomised controlled trials (25 928 participants) from 1991 up to Nov 30, 2007, which compared any of the following antidepressants at… CONTINUE READING
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