Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia.

@article{Zervos2004ComparativeEA,
  title={Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia.},
  author={Marcus John Zervos and Lionel A. Mandell and Peter S. Vrooman and Charles P. Andrews and Andrew R McIvor and Ramzan H Abdulla and Pascal J de Caprariis and Charles Knirsch and Guy W. Amsden and Michael S. Niederman and Hartmut M Lode},
  journal={Treatments in respiratory medicine},
  year={2004},
  volume={3 5},
  pages={329-36}
}
OBJECTIVE To compare the efficacy and tolerability of ceftriaxone plus azithromycin with those of levofloxacin in the treatment of hospitalized patients with moderate to severe community-acquired pneumonia (CAP). DESIGN Randomized, open-label multicenter trial with 1 : 1 treatment allocation in an inpatient setting. PATIENTS 212 male or female inpatients with a clinical diagnosis of CAP were included in the study. In each treatment group >50% of patients had a pneumonia severity index of IV… CONTINUE READING

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