Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

@article{Crescenzo2022ComparativeEO,
  title={Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis},
  author={Franco De Crescenzo and Gian Loreto D’Al{\`o} and Edoardo Giuseppe Ostinelli and Marco Ciabattini and Valeria Di Franco and Norio Watanabe and Ayse Kurtulmus and Anneka Tomlinson and Zuzana Mitrova and Francesca Foti and Cinzia del Giovane and Digby J. Quested and Philip J. Cowen and Corrado Barbui and Laura Amato and Orestis Efthimiou and Andrea Cipriani},
  journal={The Lancet},
  year={2022},
  volume={400},
  pages={170-184}
}
6 Citations

Figures from this paper

References

SHOWING 1-10 OF 52 REFERENCES

Vitruvian plot: a visualisation tool for multiple outcomes in network meta-analysis

TLDR
The Vitruvian plot is presented, which graphically presents absolute estimates and relative performance of competing interventions against a common comparator for several outcomes of interest.

Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials

TLDR
Reporting bias persists but appears to have diminished for newer, compared to older, antidepressants, according to journal-based meta-analyses.

Prevalent, incident, and persistent insomnia in a population-based cohort tested before (2018) and during the first-wave of COVID-19 pandemic (2020)

TLDR
The COVID-19 pandemic is associated with significant increases in insomnia and psychological symptoms compared to the pre-pandemic period, and large scale public sleep and mental health intervention programs should be prioritized during and after a pandemic.

Comparative Efficacy and Safety of Hypnotics for Insomnia in Older Adults: A Systematic Review and Network Metaanalysis.

TLDR
Considering study quality and the potential adverse effects of benzodiazepines and nonbenzodiazepine seems to be the optimal pharmacotherapy for the improvements of total sleep time and sleep efficiency.

Incidence, Persistence, and Remission Rates of Insomnia Over 5 Years

This cohort study assess the incidence, persistence, and remission rates of insomnia over a 5-year period in a population-based sample in Canada.

Clinical pharmacology, efficacy, and safety of orexin receptor antagonists for the treatment of insomnia disorders

TLDR
ORAs have the potential to revolutionize the pharmacological treatment of insomnia because they not only improve sleep, but, in addition, appear to have no dependence – and tolerance-inducing effects, which makes them suitable for long-term-treatment.

CINeMA: An approach for assessing confidence in the results of a network meta-analysis

TLDR
A methodological framework to evaluate confidence in the results from network meta-analyses, Confidence in Network Meta-Analysis (CINeMA), when multiple interventions are compared is presented, which improves transparency and avoids the selective use of evidence when forming judgments, thus limiting subjectivity in the process.
...