Comparative effects of methylphenidate and thioridazine in hyperkinetic children. I. Clinical results.

@article{GittelmanKlein1976ComparativeEO,
  title={Comparative effects of methylphenidate and thioridazine in hyperkinetic children. I. Clinical results.},
  author={Rachel Gittelman-Klein and Donald F. Klein and Simone Katz and Kishore R. Saraf and Erica Pollack},
  journal={Archives of general psychiatry},
  year={1976},
  volume={33 10},
  pages={1217-31}
}
The effects of three pharmacological treatments, methylphenidate hydrochloride, thioridazine hydrochloride, a methylphenidate/thioridazine combination, and placebo were studied in outpatient hyperkinetic children rated hyperactive both in school and at home or clinic. Active treatment lasted 12 weeks; placebo lasted four weeks. Significant clinical improvement was obtained in a variety of settings--all treatments were superior to placebo on ratings filled out by parents, teachers, and clinic… CONTINUE READING

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