Comparative effects of levofloxacin and ofloxacin on the normal oral and intestinal microflora.

@article{Edlund1997ComparativeEO,
  title={Comparative effects of levofloxacin and ofloxacin on the normal oral and intestinal microflora.},
  author={Charlotta Edlund and Svante Sj{\"o}stedt and Carl Erik Nord},
  journal={Scandinavian journal of infectious diseases},
  year={1997},
  volume={29 4},
  pages={383-6}
}
The aim of the study was to study the ecological effects of levofloxacin, compared to that of ofloxacin, on the oral and intestinal human microflora. 10 healthy volunteers received levofloxacin (500 mg) and 10 subjects were given ofloxacin (400 mg) perorally, once daily for 7 days. Saliva and stool samples were obtained prior to drug administration, during administration (days 2, 4 and 7), and after withdrawal of the agents (days 9, 11, 14 and 21). The concentrations of levofloxacin and… CONTINUE READING

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