Comparative effects of fluoxetine, amitriptyline and serotonin on functional motor recovery after sensorimotor cortex injury.

@article{Boyeson1994ComparativeEO,
  title={Comparative effects of fluoxetine, amitriptyline and serotonin on functional motor recovery after sensorimotor cortex injury.},
  author={Michael G. Boyeson and Robert L Harmon and Jayne L Jones},
  journal={American journal of physical medicine & rehabilitation},
  year={1994},
  volume={73 2},
  pages={76-83}
}
A recent investigation of the effects of the antidepressants desipramine and trazodone on behavioral recovery in brain-injured animals suggested that antidepressants, which act to increase noradrenergic activity in the brain, may facilitate the rate of recovery, whereas those that act to increase serotonergic (5-HT) activity may hinder recovery and reinstate deficits in recovered animals. The present study was designed to evaluate these findings further by assessing the effect of a single… CONTINUE READING

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