Comparative effects of cadmium, copper, paraquat and benzo[a]pyrene on the actin cytoskeleton and production of reactive oxygen species (ROS) in mussel haemocytes.

@article{GmezMendikute2003ComparativeEO,
  title={Comparative effects of cadmium, copper, paraquat and benzo[a]pyrene on the actin cytoskeleton and production of reactive oxygen species (ROS) in mussel haemocytes.},
  author={Amagoia G{\'o}mez-Mendikute and Miren Pilar Cajaraville},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2003},
  volume={17 5-6},
  pages={539-46}
}
The immune defence of mussels is comprised of cell-mediated and humoral mechanisms, in which haemocytes or blood cells play a key role. Environmental pollutants such as metallic and organic xenobiotics exert immunotoxical effects on aquatic organisms. Some of these xenobiotics are known to give rise to highly reactive oxygen species (ROS), thereby leading to oxidative damage to tissue macromolecules including DNA, proteins and lipids. Previously we have detected enhancement of ROS production… CONTINUE READING

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