Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines

@article{Campbell2005ComparativeEO,
  title={Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines},
  author={Sharon E. Campbell and William L. Stone and Steven A. Lee and Sarah G Whaley and Hongsong Yang and Min Ru Qui and Paige M. Goforth and Donovan Sherman and Derek McHaffie and Koyamangalath Krishnan},
  journal={BMC Cancer},
  year={2005},
  volume={6},
  pages={13 - 13}
}
Mediterranean societies, with diets rich in vitamin E isoforms, have a lower risk for colon cancer than those of northern Europe and the Americas. Vitamin E rich diets may neutralize free radicals generated by fecal bacteria in the gut and prevent DNA damage, but signal transduction activities can occur independent of the antioxidant function. The term vitamin E represents eight structurally related compounds, each differing in their potency and mechanisms of chemoprevention. The RRR… CONTINUE READING
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