Comparative effects of 17β-estradiol, raloxifene and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice

@article{Cano2007ComparativeEO,
  title={Comparative effects of 17β-estradiol, raloxifene and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice},
  author={Ampaeli Cano and Sonia Dap{\'i}a and Inmaculada Noguera and Bego{\~n}a Pineda and Carlos Hermenegildo and R. del Val and Jos{\'e} Ram{\'o}n Caeiro and Miguel A. Garc{\'i}a-P{\'e}rez},
  journal={Osteoporosis International},
  year={2007},
  volume={19},
  pages={793-800}
}
This study assessed the effect of estradiol, raloxifene and genistein on the preservation of bone 3D-microarchitecture and volumetric bone mineral density (vBMD) in the ovariectomized mouse model. Our results indicated that raloxifene was more effective in preserving bone ovariectomized-induced changes, the advantage being concentrated in both bone microarchitecture and vBMD. This study assessed the effect of different estrogen receptor (ER) agonists on the preservation of bone 3D… CONTINUE READING