Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis.

@article{Singh2015ComparativeEO,
  title={Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis.},
  author={Siddharth Singh and Rohan Khera and Alina M. Allen and Mohammad Hassan Murad and R Loomba},
  journal={Hepatology},
  year={2015},
  volume={62 5},
  pages={1417-32}
}
UNLABELLED We performed a Bayesian network meta-analysis combining direct and indirect treatment comparisons to assess the comparative effectiveness of pharmacological agents for the treatment of nonalcoholic steatohepatitis (NASH). Through systematic literature review, we identified nine randomized, controlled trials (RCTs) including 964 patients with biopsy-proven NASH, comparing vitamin E, thiazolidinediones (TZDs), pentoxifylline, or obeticholic acid to one another or placebo. The primary… CONTINUE READING