Comparative effectiveness of mepolizumab and omalizumab in severe asthma: An indirect treatment comparison.

BACKGROUND Severe asthma is a heterogeneous disease. Patients with both eosinophilic and allergic asthma phenotypes may be eligible for treatment with mepolizumab and omalizumab. Evidence on the relative effectiveness of these treatments in this 'overlap' population would be informative for clinical and payer decision making. METHODS A systematic… (More)