Comparative effect of chronic bombesin, gastrin-releasing peptide and caerulein on the rat pancreas

@article{Damg1988ComparativeEO,
  title={Comparative effect of chronic bombesin, gastrin-releasing peptide and caerulein on the rat pancreas},
  author={Christiane Damg{\'e} and Amor Hajri and Evelyne F. Lhoste and Marc Aprahamian},
  journal={Regulatory Peptides},
  year={1988},
  volume={20},
  pages={141-150}
}
This study was designed to compare, on a molar basis, the effect of chronic bombesin, gastrin-releasing peptide (GRP) and caerulein on pancreatic growth in the rat. These 3 peptides were administered s.c. 3 times daily for 4 days at the following concentrations: 0.036, 0.36, 3.6 and 7.2 nmol/kg of body weight. Bombesin and GRP induced pancreatic growth in a dose-dependent manner from 3.6 nmol/kg. This growth was characterized by an increase in pancreatic weight, its protein and RNA contents but… Expand
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TLDR
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