Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: a randomized, double-blind trial of olanzapine versus low doses of haloperidol.

@article{Keefe2004ComparativeEO,
  title={Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: a randomized, double-blind trial of olanzapine versus low doses of haloperidol.},
  author={Richard S. E. Keefe and Larry J. Seidman and Bruce K. Christensen and Robert M. Hamer and Tonmoy Sharma and M. M. Sitskoorn and Richard R. J. Lewine and Deborah A. Yurgelun-Todd and Ruben C. Gur and Mauricio Tohen and Gary D. Tollefson and Todd M Sanger and Jeffrey A. Lieberman},
  journal={The American journal of psychiatry},
  year={2004},
  volume={161 6},
  pages={985-95}
}
OBJECTIVE The effect of antipsychotic medication on neurocognitive function remains controversial, especially since most previous work has compared the effects of novel antipsychotic medications with those of high doses of conventional medications. This study compares the neurocognitive effects of olanzapine and low doses of haloperidol in patients with first-episode psychosis. METHOD Patients with a first episode of schizophrenia, schizoaffective disorder, or schizophreniform disorder (N=167… CONTINUE READING

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