Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle.

@article{Lifschitz2000ComparativeDO,
  title={Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle.},
  author={Adrian Luis Lifschitz and Guillermo L Virkel and Juan Manuel Sallovitz and Jean Francois P. Sutra and Pierre Galtier and Michel Alvinerie and Carlos E. Lanusse},
  journal={Veterinary parasitology},
  year={2000},
  volume={87 4},
  pages={
          327-38
        }
}
Pharmacokinetic studies have been used traditionally to characterize drug concentration profiles achieved in the bloodstream. However, endectocide molecules exert their persistent and broad spectrum activity against parasites localized in many different tissues. The aim of this study was to compare the distribution of ivermectin (IVM) and doramectin (DRM) to different tissues in which parasites are found following subcutaneous administration to calves. Holstein calves weighing 120-140 kg were… CONTINUE READING
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