Comparative cryo‐electron tomography of pathogenic Lyme disease spirochetes

@article{Kudryashev2009ComparativeCT,
  title={Comparative cryo‐electron tomography of pathogenic Lyme disease spirochetes},
  author={M. Kudryashev and M. Cyrklaff and W. Baumeister and M. Simon and R. Wallich and F. Frischknecht},
  journal={Molecular Microbiology},
  year={2009},
  volume={71}
}
  • M. Kudryashev, M. Cyrklaff, +3 authors F. Frischknecht
  • Published 2009
  • Biology, Medicine
  • Molecular Microbiology
  • Spirochetes of the Borrelia burgdorferi sensu lato group, the causative agents of Lyme borreliosis, exhibit a complex biology evolved in its zoonotic cycle. Cryo‐electron tomography was used to investigate structural features of three species, B. burgdorferi, B. garinii and B. afzelii, known to cause different clinical manifestations in humans. All three organisms revealed an overall similar architecture and showed different numbers of periplasmic flagellar filaments, polar periplasmic void… CONTINUE READING
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