Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults.

@article{Meador1995ComparativeCE,
  title={Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults.},
  author={Kimford J. Meador and David W. Loring and Ernest Eugene Moore and William O B Thompson and Margaret Nichols and R E Oberzan and Mikhail Durkin and Brittany Gallagher and Don W. King},
  journal={Neurology},
  year={1995},
  volume={45 8},
  pages={1494-9}
}
The relative effects of antiepileptic drugs (AEDs) on cognition are controversial. We compared the cognitive effects of phenobarbital, phenytoin, and valproate in 59 healthy adults using a randomized, double-blind, incomplete-block, crossover design. Cognitive assessments were conducted at baseline, after 1 month on each drug (two AEDs per subject), and at… CONTINUE READING