Comparative carcinogenicity of ethylene thiourea with or without perinatal exposure in rats and mice.

@article{Chhabra1992ComparativeCO,
  title={Comparative carcinogenicity of ethylene thiourea with or without perinatal exposure in rats and mice.},
  author={Rajendra S. Chhabra and Susie Eustis and Joseph K. Haseman and Pat Kurtz and Betsy D. Carlton},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1992},
  volume={18 3},
  pages={405-17}
}
Chronic toxicity and carcinogenicity studies of ethylene thiourea (ETU), 97% pure, were conducted in F344/N rats and B6C3F1 mice of each sex. The major objective of the study was to determine if incorporation of perinatal exposure, in addition to the conventional exposure of young adult animals for 2 years, enhances the sensitivity of the bioassay in identification of the carcinogenic potential of chemicals when compared to the conventional exposure of animals to a chemical for 2 years, usually… CONTINUE READING

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