Comparative biology of sperm factors and fertilization‐induced calcium signals across the animal kingdom

@article{Kashir2013ComparativeBO,
  title={Comparative biology of sperm factors and fertilization‐induced calcium signals across the animal kingdom},
  author={J. Kashir and R. Deguchi and C. Jones and K. Coward and S. Stricker},
  journal={Molecular Reproduction and Development},
  year={2013},
  volume={80}
}
Fertilization causes mature oocytes or eggs to increase their concentrations of intracellular calcium ions (Ca2+) in all animals that have been examined, and such Ca2+ elevations, in turn, provide key activating signals that are required for non‐parthenogenetic development. Several lines of evidence indicate that the Ca2+ transients produced during fertilization in mammals and other taxa are triggered by soluble factors that sperm deliver into oocytes after gamete fusion. Thus, for a broad… Expand
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